Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 10 G
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Tos-PEG3 is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- Utilized in the synthesis of PROTACs.
- Can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
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Medchemexpress LLC PEG3-C4-OBn | 2381196-79-6 | 99.3% | 50 MG
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PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. It can be used in the synthesis of the PROTAC SGK3 degrader-1, a potent SKG3 degrader based on PROTAC.
- Polyethylene glycol (PEG)-based PROTAC linker
- Used in synthesis of PROTAC SGK3 degrader-1
- Potent SKG3 degrader
- Related to cancer research
- Related to cancer targeted therapy
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Medchemexpress LLC N3-PEG3-CH2CH2-Boc | 252881-73-5 | ≥98.0% | 303.35 g·mol⁻¹ | C13H25N3O5 | 250 MG
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N3-PEG3-CH2CH2-Boc is a Boc-protected, azide-terminated PEG3 linker used in conjugation chemistry for synthesizing PROTACs and antibody-drug conjugates. It contains a three-unit polyethylene glycol spacer with an azide functional group that enables click chemistry reactions such as copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC).
- Boc-protected azide terminus for selective conjugation.
- Three-unit PEG spacer provides flexibility and improves solubility.
- Compatible with CuAAC and SPAAC click reaction methodologies.
- High purity suitable for synthetic applications (≥98.0%).
- Available in multiple pack sizes, including 250 MG.
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Medchemexpress LLC N-(Boc-PEG3)-N-bis(PEG2-alcohol) | 2055042-60-7 | C25H52N2O11 | 50 MG
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N-(Boc-PEG3)-N-bis(PEG2-alcohol) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds that contain two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Dbco-nhco-peg3-fmoc | 00-00-0 | 96.9% | C42H43N3O7 | 10MG
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DBCO-NHCO-PEG3-Fmoc is a DBCO-functionalized PEG3 linker with an Fmoc-protected amine designed for use as a click-chemistry reagent in PROTAC synthesis and bioconjugation. It participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing partners, offering modular attachment and improved handling for linker assembly.
- Click-reactive DBCO group enables strain-promoted alkyne-azide cycloaddition (SPAAC).
- Peg3 spacer improves solubility and reduces steric hindrance.
- Fmoc-protected amine allows compatibility with solid-phase and solution-phase synthesis workflows.
- High purity suitable for research applications.
- Stable as powder at -20°C for extended storage and recommended cold storage in solution.
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Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | MFCD20134131 | >97.0% | 263.29 g/mol | C10H21N3O5 | 250 MG
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Azido-PEG5-alcohol is a 5-unit polyethylene glycol (PEG) linker bearing an azide and a terminal hydroxyl group, used as a click-chemistry reagent and as a non-cleavable PEG spacer in conjugation and PROTAC synthesis. Purity is ≥97.0%, molecular weight is 263.29 g/mol, and CAS number is 86770-68-5.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
- Compatible with strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN.
- Non-cleavable 5-unit PEG spacer to improve solubility and flexibility.
- Available in multiple sizes, including 250 mg.
- High purity suitable for synthetic and conjugation applications.
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Medchemexpress LLC Azido-PEG3-SS-PEG3-azide | 1310827-27-0 | 99.3% | C16H32N6O6S2 | 10MG
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Azido-PEG3-SS-PEG3-azide is a symmetric, cleavable polyethylene glycol (PEG)-based bifunctional linker bearing terminal azide groups and a central disulfide bond. It is designed for bioconjugation and PROTAC synthesis, enabling both copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), while allowing reductive cleavage for controlled release.
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Medchemexpress LLC Mal-PEG3-NH2 TFA | 2830214-77-0 | 99.1% | 386.32 g/mol | C14H21F3N2O7 | 50 MG
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Mal-PEG3-NH2 TFA is a linear, heterobifunctional polyethylene glycol (PEG) crosslinker supplied as the trifluoroacetic acid (TFA) salt. It contains a maleimide at one end and a primary amine at the other, enabling thiol-to-amine conjugation and use as a non-cleavable linker in PROTAC and bioconjugation workflows. For research use only.
- Provides maleimide and primary amine reactive groups for orthogonal conjugation.
- PEG3 spacer improves aqueous solubility and reduces steric hindrance.
- TFA salt form enhances stability and handling compared with the free base.
- Non-cleavable linker suitable for stable conjugates and PROTAC constructs.
- High purity (>99%) for consistent conjugation performance.
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eMolecules 756526-03-1 | Bis-PEG5-NHS ester | Broadpharm | MFCD11041118 | 532.499 | C22H32N2O13 | 98.000 | O=C(CCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 1g | 112541631
Bis-PEG5-NHS ester | Broadpharm | 756526-03-1 | MFCD11041118 | 532.499 | C22H32N2O13 | 98.000 | O=C(CCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 1g | 112541631
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Medchemexpress LLC Bromoacetamido-PEG3-C2-Boc | 1807537-33-2 | C15H28BrNO6 | 250 MG
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Bromoacetamido-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs are composed of two different ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein. PROTACs work by utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Available in various quantities
- Appears as a colorless to light yellow liquid
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Medchemexpress LLC DBCO-PEG3-acid | 2754384-59-1 | 98.35% | 508.56 | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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DBCO-PEG3-acid is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- Non-cleavable 3 unit PEG ADC linker
- Contains a DBCO group for strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Azido-PEG5-CH2CO2-NHS | 2144777-77-3 | 97% | C16H26N4O9 | 250 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is a click chemistry reagent containing an Azide group, which allows it to undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker for synthesis
- Click chemistry reagent with azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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STREM CHEMICALS INC 2 -DICYCLOHEXYLPHOSPHIN 2G
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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NC2893984 2 -DICYCLOHEXYLPHOSPHIN 2G
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AURUM PHARMATECH INC 2-FLUORO-4-TRIMETHYLSIL / 10G
NC3244006 2-FLUORO-4-TRIMETHYLSIL / 10G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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STREM CHEMICALS INC R 6 6 BIS DIPHENYLPHOSPINO 2
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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NC3252559 R 6 6 BIS DIPHENYLPHOSPINO 2
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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